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Benzophenone-4 (Sulisobenzone)


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Part Number:SCR-BENZO4-01

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HS Code 3304100000
Description: Water-soluble UVA and UVB filter. Only short UVA (UVA-2, 290-360 nm) but not long UVA are filtered. Synonyms: Sulisobenzone, 1-phenol-4-sulfonic acid. Highly stable, does not degrade in sunlight but protects other UV blocking agents from UV-induced degradation. Benzophenone-4 is readily soluble in water, propylene glycol, glyerin, ethanol and isopropyl alcohol. Due to its high acidity (pH < 2.5 in a 1% solution), a neutralizing agent (e.g. triethanolamine) must be added to elevate the pH to >3.5. Yellow to beige powder.

CAS: 4065-45-6

INCI Name: Benzophenone-4

  • Water-soluble UVA & UVB filter. Used primrily as UVA filter
  • Should be combined with other sunscreens (e.g. octocrylene, homosalate, ethylhexyl salicylate, OM-cinnamate) for effective UVB protection. Benzophenone-4 provides inadequate UVB protection when used alone.
  • Does not penetrate the skin to a large degree, but enhances the ability of other ingredients to penetrate
  • Helps to stabilize UV sensitive formulations such as hair dyes, hair sprays and color enhanced formulations
  • Provides protection of colorants against fading and help stabilize fragrances and active ingredients against oxidation

Use: Incorporate into water phase (pH 1.2-2.2). Allowed use levels: USA 10% (when used alone; 5-10% when used in combination), Brazil 10%, Japan 10%, EU 5%. For external use only.

Applications: Sun care products, color cosmetics with sun protection, various cosmetics & fragrances for product protection.

Country of Origin: USA

Raw material source: Benzophenone-3

Manufacture: Benzophenone-4 is prepared via sulfonation of benzophenone-3. The product is then purified by precipitation from aqueous hydrochloric acid, isolated by centrifugation, washed with acidic water, and dried.

Animal Testing: Not animal tested

GMO: GMO free (does not contain plant-derived components)

Vegan: Does not contain animal-derived components

Regulatory Information: Sunscreens are registered as API (Active Pharmaceutical Ingredient) or OTC-drug with the FDA. This means that, if you want to sell products containing a sunscreen, your facility must be registered with the FDA and operate under cGMP guidelines. Further information about the FDA regulation of sunscreens can be found here.

Documents: SDS, Fact Sheet, Certificate of Analysis

For California Customers: Under California's Safe Drinking Water and Toxic Enforcement Act, better known as OEHHA Prop 65, we are required to place a warning to this product since the OEHHA believes that benzophenone (CAS 119-61-9), a substance used in the production of benzophenone-4, is cancerogenic.

This product can expose you to chemicals including Benzophenone, which is known to the State of California to cause cancer. For more information, go to


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