High-molecular weight hyaluronic acid (HA) does not readily dissolve in water as it binds water very quickly. Thus, HA needs to be carefully sprinkled into the water under constant high-speed stirring (preferably with a hand mixer or vortex mixer). Typical concentration is at 0.1 - 2% of HA (equals 1g of HA in 100ml of water). The mixture starts then thickening quickly and becomes a gel. At that point no additional HA can be added as there is no water left for HA to be dissolved in. Any additional HA would only form lumps. Here is a video on how to dissolve HA in water: https://www.youtube.com/watch?v=xwy2IT_Ig5c

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